URL 3S Pharma Machinery Inc. is a leading Supplier and Manufacturer of Granulation Line with Isolator in Ahmedabad.
We offer technologically advanced Granulation Line with Isolator systems engineered for the safe manufacturing of highly potent pharmaceutical products.
Built to meet OEB 4 and OEB 5 containment standards, the system integrates essential Oral Solid Dosage (OSD) equipment inside a fully enclosed negative-pressure isolator.
Engineered for pharmaceutical, biotech, and nutraceutical industries, this integrated solution minimizes contamination risks, enhances process efficiency, and supports global GMP compliance.
Complete Integrated Pharmaceutical Processing Line:
Our containment solutions combine every essential granulation process into one automated and enclosed production system.
1. Rapid Mixer Granulator (RMG)
The Rapid Mixer Granulator efficiently converts powder blends into uniform granules with consistent density and excellent flow characteristics.
Key Advantages:
• Fast wet granulation
• Consistent particle formation
• Improved powder flowability
• High-speed mixing technology
• Reliable batch consistency
2. Fluid Bed Dryer (FBD)
The integrated Fluid Bed Dryer ensures rapid and uniform moisture removal while maintaining product quality throughout the drying cycle.
Features:
• Uniform drying performance
• 12-Bar pressure-resistant design
• HEPA-filtered drying air
• Energy-efficient operation
• Controlled drying process
3. Wet & Dry Cone Milling System
Designed for precision granule sizing, the cone mill delivers uniform particle distribution while maintaining a dust-free contained process.
Benefits:
• Closed-loop milling
• Uniform particle sizing
• Reduced material wastage
• Improved downstream processing
• High containment operation
4. Vacuum Powder Transfer System
The enclosed vacuum transfer system enables safe movement of pharmaceutical powders without exposing operators or products to contamination.
Highlights:
• Dust-free powder transfer
• Fully enclosed conveying
• No manual handling
• Prevents cross-contamination
• Improved process safety
5. Pharmaceutical Blending Unit
Our integrated blending system produces homogeneous powder mixtures before tablet compression or capsule filling.
Available configurations include:
• IBC Blender
• Fixed Bowl Blender
6. Integrated CIP & WIP Cleaning Technology
The automated cleaning system significantly reduces cleaning time while simplifying validation procedures.
Includes:
• Cleaning-In-Place (CIP)
• Wash-In-Place (WIP)
• Automated cleaning cycles
• Reduced equipment downtime
• Faster production turnaround
Flexible Batch Processing Capacity:
Our systems are available for research laboratories, pilot facilities, and commercial pharmaceutical production.
- 200 g – 2 kg – Research & Development
- 600 g – 5 kg – Pilot Manufacturing
- 2 kg – 15 kg – Commercial Production
Customized batch capacities are available based on customer requirements.
High-Containment Safety Features:
Every Granulation Line with Isolator is developed to maximize containment performance while maintaining operator comfort and regulatory compliance.
OEB 4 / OEB 5 Protection
• Operator exposure below 1 µg/m³
• Fully enclosed processing chamber
• High-containment pharmaceutical production
• Enhanced environmental protection
Negative Pressure Barrier System
• Operating pressure: –50 to –80 Pa
• Continuous pressure monitoring
• Stable airflow management
• Safe containment environment
Automatic Inflatable Air Seals
• Automatic sealing
• Leak-free interfaces
• Safety interlocks
• Reliable containment integrity
Contained Material Transfer Options
Safe material transfer can be achieved using:
• Continuous PE Liner
• Alpha Beta Transfer System
• Rapid Transfer Ports (RTP)
Advanced BIBO Filtration System
• F9 Pre-Filters
• H13/H14 HEPA Filters
• Safe maintenance
• Contamination-free filter replacement
Pharmaceutical Grade Hygienic Construction
• SS316L product contact parts
• Mirror-polished surfaces
• Crevice-free construction
• Rounded internal corners
• Easy cleaning design
Ergonomic Glove Port Design
• Comfortable operation
• Reduced contamination risk
• Safe intervention
• Improved operator safety
Smart Automation Platform
Available options:
• PLC & HMI Controls
• Recipe Management
• Alarm Monitoring
• Data Logging
• SCADA Integration
• Optional 21 CFR Part 11 Compliance
Industries & Applications:
The Granulation Line with Isolator is suitable for:
- HPAPI Manufacturing
- Oncology Medicines
- Cytotoxic Drug Processing
- Hormonal Pharmaceutical Production
- Sterile Granulation
- Non-Sterile Granulation
- Tablet Manufacturing
- Capsule Manufacturing
- Oral Solid Dosage (OSD)
- Nutraceutical Processing
- Chemical Powder Manufacturing
Complete High-Containment Pharmaceutical Solutions:
In addition to Granulation Lines with Isolators, 3S Pharma Machinery Inc. supplies complete containment solutions including:
• Wet Granulation Systems
• Dry Granulation Lines
• Roller Compaction Systems
• Tablet Compression Isolators
• Tablet Coating Isolators
• Capsule Filling Isolators
• Vacuum Tray Dryer (VTD) Isolators
• Dispensing Booths
• Sampling Booths
• High-Containment Transfer Systems
• Pharmaceutical Packaging Containment Solutions
Working alongside globally recognized OEM partners, we deliver customized turnkey solutions that improve manufacturing safety, ensure regulatory compliance, and optimize pharmaceutical production performance.
Frequently Asked Questions:
What is a Granulation Line with Isolator?
A Granulation Line with Isolator is a fully enclosed pharmaceutical manufacturing system designed to safely process potent drug compounds while minimizing operator exposure.
Which containment standards does the system meet?
The system is available in OEB 4 and OEB 5 containment configurations, making it suitable for highly potent pharmaceutical manufacturing.
Which machines can be integrated?
The line can include a Rapid Mixer Granulator, Fluid Bed Dryer, Cone Mill, Blender, Vacuum Transfer System, and automated CIP/WIP cleaning system.
Is the system suitable for HPAPI production?
Yes. It is specifically designed for HPAPI, oncology, cytotoxic, hormonal, and other high-potency pharmaceutical products.
Can the equipment be customized?
Absolutely. Batch capacity, containment level, automation features, and equipment configuration can all be tailored to your production requirements.
URL 3S Pharma Machinery Inc. is a leading Supplier and Manufacturer of Granulation Line with Isolator in Ahmedabad, India, other locations including: Navrangpura, Satellite, Vastrapur, Bodakdev, Thaltej, Prahlad Nagar, Bopal, Gota, Chandkheda, Motera, Sabarmati, Ranip, Naranpura, Memnagar, Paldi, Ellisbridge, Ambawadi, Maninagar, Vatva, Narol, Odhav, Nikol, Vastral, Sarkhej, Sanand, Changodar, Bavla, Dholka, Gandhinagar, Surat, Vadodara, Rajkot, Jamnagar, Bhavnagar, Bharuch, Ankleshwar, Vapi, Navsari, Mehsana, Morbi, Junagadh, Bhuj, Gandhidham, Anand, Nadiad, Porbandar, Veraval, Surendranagar, Amreli, Palanpur, Patan, Deesa, Godhra, Dahod, Himatnagar, Kutch and nearby industrial regions.
Contact Details:
URL 3S Pharma Machinery Inc.
Call Us: +91 87582 51079
Email: info@url3s.com
For more information, please feel free to contact us.
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