URL 3S Pharma Machinery Inc. is a trusted Supplier and Manufacturer of Complete Integrated Granulation Line in Indore, Madhya Pradesh, India.
A Complete Integrated Granulation Line helps pharmaceutical manufacturers streamline solid dosage production by connecting powder mixing, wet granulation, drying, and tablet coating within a coordinated processing system. This integrated approach improves workflow management, supports consistent batch processing, and reduces the need for repeated manual material transfers.
Designed for pharmaceutical, nutraceutical, and related manufacturing facilities, the system combines a High Shear Mixer Granulator (HSMG), Fluid Bed Dryer (FBD), and Tablet Coating Machine. Each unit performs a specific processing function while working as part of a planned production line.
With hygienic construction, automated controls, and flexible capacity options, an integrated granulation solution supports manufacturers in managing production requirements from laboratory development to commercial-scale manufacturing.
Advantages of Coordinating Granulation, Drying and Coating:
An integrated system can help pharmaceutical manufacturers improve process coordination without treating each machine as an independent production step.
- Reduces unnecessary material movement between equipment.
- Supports repeatable processing parameters across batches.
- Helps improve production planning and equipment utilization.
- Reduces manual intervention where automated transfer is available.
- Supports better control of moisture and coating operations.
- Provides flexibility for different product formulations.
- Helps manufacturers plan capacity expansion and process upgrades.
High Shear Mixer Granulator: Controlled Mixing and Granule Formation
The High Shear Mixer Granulator (HSMG) combines powder blending and wet granulation in a single processing vessel. Its impeller and chopper help distribute ingredients and develop granules with suitable physical characteristics.
Key engineering features include:
- High-performance impeller and chopper assemblies.
- SS 316L product-contact components, as specified.
- Integrated powder mixing and wet granulation operations.
- PLC and HMI-based process controls.
- Pneumatic discharge options for controlled material transfer.
- Heavy-duty construction for industrial production.
- Capacity options from 2 litres to 1,200 litres, subject to the selected model.
Fluid Bed Dryer: Efficient Moisture Removal
The Fluid Bed Dryer (FBD) removes moisture from wet granules by suspending and moving the material through a controlled stream of heated air. Proper airflow and temperature control help achieve the specified drying endpoint while protecting product quality.
Important features include:
- Pharmaceutical-grade stainless steel construction.
- SS 316L product-contact surfaces, as specified.
- Air Handling Unit with suitable filtration stages.
- Pre-filters, microfilters, and HEPA filtration options according to system design.
- Controlled airflow and drying temperature.
- Automated process monitoring.
- Available model options from FBD-1 to FBD-500, with indicative batch capacities from 1 kg to 500 kg.
Actual drying capacity depends on the product, initial moisture content, required final moisture, airflow, and operating conditions.
Tablet Coating Machine: Uniform Surface Finishing
The Tablet Coating Machine applies a controlled coating layer to tablets and compatible pellets. By managing spray delivery, pan movement, and drying airflow, the system helps manufacturers achieve the required coating appearance and product performance.
Key features include:
- cGMP-oriented hygienic design.
- PLC, HMI, or SCADA-based automation options.
- Precision spray guns and peristaltic dosing systems.
- Perforated coating pan with variable-speed control.
- Controlled drying airflow.
- Touchscreen operation.
- Capacity options from 0.5 kg laboratory models to 500 kg production models, depending on configuration.
The appropriate coating machine depends on tablet dimensions, batch size, coating formulation, and the required finish.
Pharmaceutical and Related Manufacturing Applications:
A Complete Integrated Granulation Line serves production facilities that manufacture solid or granulated products requiring controlled mixing, moisture reduction, and coating.
- Pharmaceuticals: Granules and coated tablets for solid dosage manufacturing.
- Nutraceuticals: Suitable granulated supplements and coated dosage forms.
- Herbal and Ayurvedic products: Processing of compatible herbal formulations.
- Contract manufacturing: Production lines for multiple customer formulations.
- Biotechnology: Selected compatible formulations requiring granulation and drying.
- Food processing: Suitable granular products and coating applications.
- Chemical manufacturing: Compatible products that require controlled granulation and drying.
- Research and development: Laboratory and pilot-scale process development.
Equipment suitability depends on product characteristics, cleaning requirements, regulatory obligations, and the intended manufacturing process.
Frequently Asked Questions:
Q1. What machines form a Complete Integrated Granulation Line?
The main units are a High Shear Mixer Granulator, Fluid Bed Dryer, and Tablet Coating Machine.
Q2. What is the purpose of a High Shear Mixer Granulator?
It blends powders and forms wet granules with suitable physical properties for downstream processing.
Q3. How does a Fluid Bed Dryer process granules?
It uses controlled heated airflow to remove moisture from granules.
Q4. Does the integrated line support automated control?
Yes. PLC and HMI controls, with optional SCADA and other functions, can support process monitoring and automation.
URL 3S Pharma Machinery Inc. is a trusted Supplier and Manufacturer of Complete Integrated Granulation Line in Indore, Madhya Pradesh, India Including other locations like Agar, Malwa, Alirajpur, Anuppur, Ashoknagar, Balaghat, Barwan, Betul, Bhind, Bhopal, Burhanpur, Chhatarpur, Chhindwara, Damoh, Datia, Dewas, Dhar, Dindori, East Nimar, Guna, Gwalior, Harda, Hoshangabad, Jabalpur, Jhabua, Katni, Mandla, Mandsaur, Morena, Narsinghpur, Neemuch, Niwari, Panna, Raisen, Rajgarh, Ratlam, Rewa, Satna, Sehore, Seoni, Shahdol, Shajapur, Sheopur, Shivpuri, Sidhi, Singrauli, Ujjain, Umaria, Vidisha, West Nimar.
Contact Details:
URL 3S Pharma Machinery Inc.
Call Us: +91 87582 51079
Email: info@url3s.com
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