Pharma Machinery Inc.

Photostability Chamber

Introduction

We offer advanced Photostability Chambers engineered for precise light- and temperature-controlled testing. Designed in accordance with ICH Q1B guidelines, these chambers are essential for evaluating the stability, degradation, and shelf life of pharmaceutical, cosmetic, and industrial products under simulated daylight conditions.

A Photostability Chamber is a specialized environmental testing unit that exposes samples to controlled UV and visible (LUX) light to determine the impact of prolonged illumination. These chambers are widely used in pharmaceuticals, life sciences, chemical industries, cosmetics, research laboratories, and government institutes.

We deliver accurate and repeatable testing through precise control of temperature, humidity, UV intensity, and visible light, ensuring full compliance with global regulatory standards and supporting robust stability testing protocols.

Photostability Chamber
Photostability Chamber
Photostability Chamber

Construction & Design

Our Photostability Chambers are built to deliver durability, reliability, and long-term performance. Each unit is engineered using best-in-class materials and advanced fabrication technology.

Key Construction Features

  • CNC-engineered fabrication ensures uniformity, precision, and long-lasting structural integrity.
  • Internal chamber made of high-grade stainless steel (SS 304/316) with dull or mirror finish for superior hygiene and corrosion resistance.
  • Fluorescent tubes (cool white) for visible light and UV tubes for ultraviolet exposure, fully compliant with ICH Q1B photostability testing requirements.
  • External body options:
    • Stainless Steel (GMP model)
    • GI powder-coated finish (Standard model)
  • Water- and vapor-tight inner chamber made using high-grade stainless steel.
  • Arc-welded seams for enhanced mechanical strength and durability.
  • Integrated air circulation system for uniform temperature and light distribution.
  • Comprehensive systems for heating, cooling, UV & LUX illumination, and humidity generation.
  • Double-door design:
    • Outer insulated door
    • Inner glass door for full visibility
    • Silicone gasket sealing with lock-and-key mechanism
  • Top-mounted control panel providing easy access to electrical switchgear and refrigeration components.
  • Heavy-duty castor wheels for smooth mobility.
  • Adjustable SS perforated or wire-mesh trays, electro-polished and easy to clean.
  • Other Details & Specifications

    Photostability Chamber is engineered to deliver precise, controlled, and repeatable light exposure for pharmaceutical, cosmetic, and research-based stability studies. Built with high-grade stainless steel and advanced insulation, the chamber ensures a stable internal environment while preventing any external interference during testing.

    Its intuitive and user-friendly interface makes it easy to adjust UV & LUX intensity, temperature, and humidity, ensuring accurate and reliable results. Designed with automation, safety, and regulatory compliance in mind, the chamber supports seamless photostability testing while maintaining product integrity.

    The system incorporates programmable controls, automatic light regulation, safety alarms, and a UV-protected viewing door that allows safe sample observation without interrupting the testing cycle. Offering efficiency, precision, and ease of operation, Kesar’s Photostability Chamber fully complies with ICH Q1B and simplifies light-based stability studies for professionals across industries.

    Control Systems

    Our advanced control architecture ensures accurate and consistent environmental conditions throughout the study.
    • HMI/PLC-based system provides precise regulation of temperature, humidity, UV intensity, and LUX illumination.
    • 7″ TFT HMI Display enables real-time monitoring and control of all parameters including sensors, heating & cooling utilities, and humidity system.
    • Automatic UV & LUX light control adjusts exposure based on pre-set study requirements to guarantee consistent illumination.
    • Programmable alarms for temperature/humidity deviations, door openings, power failure, or system errors ensure complete sample safety.
    • USB and Ethernet connectivity allow real-time data logging, remote monitoring, and easy compliance with regulatory documentation.
    • Rotronic 4–20 mA sensors provide high-precision measurement and control accuracy.
    • PLC with auto-tuning ensures optimized control of temperature and humidity.
    • Automatic standby system changeover for refrigeration and humidity ensures uninterrupted testing.
    • Energy-efficient design prevents hot spots and maintains uniform light distribution across the chamber.
    • Data storage and transfer capability enables exporting Date/Time, SV, PV, Door Open/Close logs, Power On/Off records, and other parameters via Ethernet or USB.

    Features

  • Designed as per ICH-Q1B Confirmatory Study Guidelines.
  • Capable of delivering ≥ 1.2 million lux-hours illumination and ≥ 200 watt-hours/sq.m near-UV exposure.
  • Online, real-time monitoring of UV & LUX exposure.
  • Automatic cycle cutoff once the programmed UV/LUX exposure requirement is achieved.
  • Provides controlled exposure conditions for drug substance and product comparison under standardized lighting.
  • Ensures accurate and reproducible environmental conditions necessary for regulated photostability studies.
  • Engineered for pharmaceutical, cosmetic, chemical, and research laboratories requiring precise light-based stability testing.
  • HMI + PLC Controller Based Enhancements

  • 7″ HMI TFT colour touchscreen with password protection for secure access.
  • Real-time display of system utilities including heating, cooling, sensors, and humidity generator status.
  • Rotronic sensors for accurate, stable monitoring of temperature and humidity.
  • PLC auto-tuning for highly precise environmental control.
  • Auto changeover to standby systems for uninterrupted operation.
  • Data logging module for Ethernet-based online monitoring and USB-based log export.
  • Integrated UV & LUX meters for accurate reading and documentation.
  • Stores Date, Time, Set Value (SV), Process Value (PV), door status, power logs, and more.
  • Optional Features

  • 21 CFR Part 11 compliant software
  • Standby cooling system
  • Standby humidity system
  • Scanner (4 temperature + 4 RH channels) for online monitoring
  • GSM alert system
  • High-security alarm system
  • Additional trays
  • HMI + PLC advanced controller package
  • Safety & Alert Systems

  • High/low temperature alarm
  • High/low humidity alarm
  • Temperature and humidity cutoff protection
  • Low water level cutoff
  • Auto changeover to standby systems
  • Door open alarm
  • Power failure alert
  • Comprehensive safety interlocks to protect samples and maintain test integrity
  • Technical Specification

    Temperature Range20°C to 60°C
    Accuracy±1.0°C
    Uniformity±2.0°C
    Control SystemPLC Based

    Material Of Construction

    ModelsCapacity (in Ltrs.)Dimensions (W X D X H)Nos. of Light Bank
    Internal
    Width X Depth X Height (mm)
    External
    Width X Depth X Height (mm)
    KGOP-227227 LTR600 X 630 X 600790 X 1070 X 12101
    KGOP-325325 LTR600 X 630 X 900790 X 1070 X 15102
    KGOP-400400 LTR600 X 630 X 1060790 X 1070 X 16702
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